Urinary excretion of exosomal organic anion transporter 5 (Oat5) increased in the rats treated with cisplatin and decreased when renal injury was ameliorated by N-acetylcysteine co-administration [213] Content of glutamyl aminopeptidase in microvesicular and exosomal fractions of urine is an early and predictive biomarker of renal dysfunction in cisplatin-induced AKI in rats [214]. Here, SLC22A10 is linked to acute kidney injury.