To further examine the role of METTL14, YTHDF2 and ALKBH5 in regulating the expression of EBV proteins, METTL14, YTHDF2 and ALKBH5 were knocked down with lentivirus carrying shRNA in EBV-positive Burkitt lymphoma cells and LcLs. The gene discussed is METTL14; the disease is Burkitt lymphoma.