CRP and rheumatoid arthritis: There was also no association between RA PRSs and plasma C-reactive protein at age 16 years (mean [SD] age at measurement, 15.5 [0.4] years) (β, 0.01; 95% CI, −0.03 to 0.04; P = .74; R2 < 0.001) or between IBD or MS PRSs and any inflammatory marker (Figure 3; eTable 6 in the Supplement).