We observed co-precipitation of pS555-ULK1 with p38 MAPK in control myotubes, and that the level of co-precipitated pS555-ULK1 dramatically increased in LCM-treated myotubes (Figure 6B), suggesting that p38 MAPK does interact with ULK1 resulting in phosphorylation of its Ser-555 residue in myocytes, and this activity is stimulated upon p38 MAPK activation by a tumor burden. This evidence concerns the gene ULK1 and neoplasm.