Moreover, 10 (such as hematopoietic cell lineage and primary immunodeficiency) and 11 (such as glutathione metabolism and cytokine-cytokine receptor interaction) KEGG pathways separately were enriched for the mRNAs in the co-expression networks for RNA set1 and RNA set2 (Table 3). This evidence concerns the gene IL18R1 and inborn error of immunity.