⬇ Ovalbumin-induced allergic asthma⬇ Inflammatory cell counts in BALF, lung total protein content and pulmonary edema ⬇ TNF-α, IL-4, and IL-13⬇ Serum lactate dehydrogenase (LDH) activity and lung malondialdehyde (MDA) content⬆ Superoxide dismutase (SOD) activity, reduced glutathione (GSH) levels and serum and lung catalase activities. The gene discussed is SOD1; the disease is allergic asthma.