The administration of CM resulted in an increase in the quantity of autophagosomes as well as significant elevations in the abundance of LC3B-II and beclin-1 and decreased p62 expression, which further supported that autophagy is involved in the pathological process of CIN and the TMP-dependent renoprotective effect against CIN. Here, BECN1 is linked to cervical squamous intraepithelial neoplasia.