Only three previous studies have analyzed rs3136558 polymorphism, which reported IL‐1B (rs3136558) was significantly associated with new‐onset diabetes after transplantation and papillary thyroid carcinoma (Ban et al., 2012; Kim et al., 2012), and a few studies have indicated the associations of rs1143630 with preeclampsia and papillary thyroid carcinoma (Ban et al., 2012; Galvão et al., 2016). This evidence concerns the gene IL1B and preeclampsia.