CXCL8 and neoplasm: As was reported, chemokines from TAMs including monocyte chemotactic protein‐1, macrophage inflammatory protein‐1α,β, macrophage derived chemokines, and IL‐8 are dedicated to tumor growth directly by interacting with their receptors.97, 98 On the other hand, chemokines from TAMs are also reported to possess the ability of attracting other cells to tumor niche, such as leukocyte and vascular endothelial cells, which make effects on tumor growth indirectly.