In current opinion, TAMs are tending to be M2‐like phenotypic due to the production of IL‐10, TGF‐β, and PGE2, which are typical markers of M2 type that promote tumor angiogenesis and tissue remodeling.76 In tumor microenvironment, many other cytokines are liberated from TAMs to promote tumor invasion, such as M‐CSF, MMPs, and EGF. The gene discussed is TGFB1; the disease is neoplasm.