IL6 and cancer: For instance, CCR5 blockage will inhibit breast cancer cells growth, resulting a decreased monocyte recruitment into developing tumors.124 Besides, the inflammatory cytokines of IL‐1β and IL‐6 can also increase the expression of their corresponding chemokine‐receptors.125 Basically, the crosstalk between TAMs and cancer cells are mediated by the chemokine‐receptor largely, but it is not fully established and requires further investigation.