The pro‐survival activity of 14‐3‐3ζ might be primarily due to its ability of sequestering diverse pro‐apoptotic proteins such as BAD, BAX, ASK1, FOXO3 or c‐Abl in multiple type of cancer.27 However, little is known whether the oncogenic potential of 14‐3‐3ζ is associated with the inhibition of induction of cancer cell senescence. This evidence concerns the gene BAX and cancer.