Since our previous study found a significant increase in the proportion of sialyl 6-sulfo LeX –expressing CCR4+ memory Th cells of asthma patients6, in the present study we assessed the expression of three carbohydrate glycans, sialyl 6-sulfo LeX, cyclic sialyl 6-sulfo LeX and sLeX, on subsets of memory Th cells and Treg cells from the peripheral blood of asthmatic children, and examined their associations with asthma severity and clinical parameters in order to better understand their potential roles in the pathogenesis of asthma. Here, CCR4 is linked to asthma.