In addition to the role of FOXF2 in promoting the bone-specific metastasis of breast cancer, we also observed a role of FOXF2 in suppressing the visceral organ metastasis of BLBC, which is consistent with our previous findings that FOXF2-deficient BLBC cells have a propensity to metastasize to visceral organs12,13. The gene discussed is FOXF2; the disease is breast carcinoma.