To investigate the role of FOXF2 in breast cancer bone metastasis, we first analyzed the FOXF2 expression pattern in the luminal and triple-negative/basal-like subtypes of breast cancer based on the GSE12777_GSE15026_GSE65194 data set of human breast cancer cell lines and the E-MTAB-365 and GSE3494 data sets of primary breast cancer tissues. Here, FOXF2 is linked to breast carcinoma.