To determine the step of virus entry impacted by CD46, mAbs 2E7 and 5C3 (anti-gH) and heparin were added to ARPE-19 cells up to 5 h post infection (hpi) with TB40/E wt (Fig. 6a) and AD169BADrUL131 (Supplementary Fig. 4a) and evaluated for virus infection. This evidence concerns the gene CD46 and viral infectious disease.