FOXO1 and cancer: This identified ATF4, FOXO1, HIF1A, MAF, MYC, and SREBP1 in FGFR-dependent cancer cells whereas ATF4 and MYC in EGFR-addicted cancer cells, which were required for the transcription of the signature genes in glycolysis or SSP (Fig. 4a, Supplementary Dataset 9).