PHGDH and non-small cell lung carcinoma: PC9 xenograft model (Fig. 2d) and a NSCLC patient-derived xenograft (PDX) model LU-01-0251 with EGFR L858R mutation (Fig. 2e, Supplementary Dataset 7) were treated with EGFR inhibitor Gefitinib or NCT503, the only PHGDH inhibitor reported to exhibit in vivo activity.