Consistent with these published data, western blot (Fig. 2b, upper panel) and RTqPCR (Supplementary Fig. 3b) analysis of a smaller panel of breast cancer cell lines revealed low levels of AKR1B10 protein and mRNA in the ER+ ZR75.1 and MCF7 lines and high levels in the basal-like BT20, MDA-MB-468 and HCC1395 lines (Fig. 2b, upper panel). Here, AKR1B10 is linked to breast cancer.