Out of 65 pairs of normal lung and lung cancer tissues analyzed, CHTM1 overexpression was noted in 6/12 (50%) squamous cell carcinomas and 36/52 (69.2%) adenocarcinomas (Fig. 6f); one large cell carcinoma sample also exhibited elevated CHTM1 levels. The gene discussed is CHCHD5; the disease is large cell carcinoma.