Wu et al. [20] found that OM could exert protective effects against liver fibrosis by inhibiting the expression of TGF-β1 and Smad3 and promoting Smad7 expression in rats induced by CCL4.Taken together, it suggests that the mechanism of OM on HSC might be associated with miR-195. The gene discussed is TGFB1; the disease is Hepatic fibrosis.