TGFB1 and colonic neoplasm: Although, most knowing biomarkers, like PD-L1, IFN-γ, IFN-γ associated immune gene signature, TGFβ/Wnt-β-catenin signaling, and CD8 T cells infiltration could be identified from the globe expression of MSI subtype colon cancer patients, some biomarkers may be not involved in MSI expression signature.