There are two reasons: one is all of them were emphasized during stage transitions of cashmere growth in skins by researchers before [2, 5]; the other is corresponding hormone-binding receptors (i.e., ESR1, IGTAV and LEPR) were on the list of upregulated genes, which strongly suggests goat DPCs are targets of estrogen, thyroid hormone, and leptin in the HF. Here, LEP is linked to hydrops fetalis.