To illustrate this situation, Fig. 5a shows a 9 kb region at the human chromosome 1p13 locus containing the noncoding region between CELSR2 and PSRC1 associated with both low-density lipoprotein (LDL) cholesterol levels and myocardial infarction (MI) in GWAS [55]. The gene discussed is PSRC1; the disease is myocardial infarction.