IGFBP3 and metastatic malignant neoplasm in the lymph nodes: In addition, patients with lymph node metastasis absent had elevated serum IGFBP‐3 levels than those of patients with lymph node metastasis present (4.73 [3.92, 5.72] vs 4.11 [2.45, 4.83] μg/mL, P = 0.02).