CEL and chronic myelogenous leukemia, BCR-ABL1 positive: Similarly, the LE score was positively associated with free CML (β = 0.044; 95% CI 0.012; 0.076) and CEL (β = 0.040; 95% CI 0.009; 0.072) but inversely with protein-bound CML (β = −0.037; 95% CI -0.060; -0.013).