To investigate the effects of starting tumour size, PD-L1 expression and antigen intensity on tumour response, we plot the time-dependent tumour size, percentage change of tumour size with respect to the starting tumour size, average number of effector T cells and mAPCs in TDLN over the 15 months by changing one parameter at a time in figures 3, –5. The gene discussed is CD274; the disease is neoplasm.