Salient features of the network are as follows: (1) Inducible knock-down of YY1 led to suppression of mitogenic pathways such as TGF signaling (both TGFA and TGFB) and c-Myc pathway, which indicates role of YY1 in proliferation of oral cancer cells. Here, TGFB1 is linked to lip and oral cavity carcinoma.