BCL2 and cervical carcinoma: In line with our findings, Zhao et al. showed that polysaccharides derived from PO induce apoptosis in cervical carcinoma U14 and HeLa cells through decreasing Bcl-2, as an anti-apoptotic protein, and increasing Bax, as an apoptotic protein, as well as increasing Bax/Bcl-2 ratio (Zhao et al., 2013[62], 2017[63]).