Both members of the cluster (miR-144-3p and miR-451a) have been respectively proposed to target21,22 inflammatory factors associated with the pathogenesis of endometriosis including PTGS2/COX226–28, TNF-α29,30, IL-1β29,30, IL-630,31, MIF23, and YWHAZ24, but the majority of emphasis has been placed upon miR-451a. This evidence concerns the gene PTGS2 and endometriosis.