Results showed that CHOW + MC (P47 phox KO) and NAFLD + MC (P47 phox KO) mice showed a significant decrease in colocalization of NLRP3/ASC II when compared to CHOW + MC and NAFLD + MC groups respectively (Fig. 9Ai–iv,C). Here, NLRP3 is linked to metabolic dysfunction-associated steatotic liver disease.