TGFBR2 and chronic kidney disease: If these genes modify bnl and MFS2 gene expression, response to microinjection of human FGF23 and tubule stone formation in flies, then their human orthologs could be used to identify novel drugs that also reduce morbidity and mortality in the human population with chronic kidney disease (CKD), which currently affects 20 Million Americans, and for whom dietary Pi is an important predictor of mortality7–9.