Mucocutaneous neuromas (hamartoma of the peripheral nerve sheath) have been reported on the face, hands, shins, and back in numerous patients with PHTS, with Starink et al. (reporting before the identification of the PTEN gene) finding them in more than half of their clinically-diagnosed patients by age 18 [15,48,101,104]. The gene discussed is PTEN; the disease is PTEN hamartoma tumor syndrome.