Meanwhile, silencing of RIPK1 expression also caused significant increases of late apoptosis cells in H358 (6.15% ± 0.23%) and LTEP-a2 (8.42% ± 1.12%) cell lines, which indicates that RIPK1 participated in the apoptotic regulatory processes in multiple NSCLC cells. Here, RIPK1 is linked to non-small cell lung carcinoma.