Bacteriophage Qβ has an RNA genome of positive polarity (such as poliovirus, foot-and-mouth disease virus, or the coronavirus causing the severe acute respiratory syndrome) of 4217 nucleotides that encodes four proteins: the A2 protein for bacterial lysis and entry, the coat protein, the A1 protein, which is present in low amounts in the capsid and expressed through incorrect reading of the stop codon of the coat protein, and the replicase that copies the RNA genome [37]. Here, GOLPH3 is linked to severe acute respiratory syndrome.