In our previous study, we have screened the total number of non-synonymous coding single nucleotide polymorphisms (SNPs) in TP53 gene and precited three deleterious coding non-synonymous SNPs rs11540654, rs17849781 and rs28934874 coding for mutations R110P, P278A, P151T in TP53 with a phenotype in breast tumors using computational tools SIFT, Polyphen-2 and MutDB. Here, TP53 is linked to breast neoplasm.