SFN and infection: Consistent with our qRT-PCR analysis (Fig 4B), infection of HDFn cells with ΔNp73β in combination with KLF4 + ΔNp63α led to increased expression of KRT14, KRT5, FLG, and SFN as compared to KLF4 + ΔNp63α with control or control alone (S4 Table).