PARK7 and Parkinson disease: Although the exact progressive degenerative mechanisms of dopaminergic neurons are not understandable, either environmental causes including exposure to insecticides, neurotoxic agents, and heavy metals, or genetic causes such as mutations of Parkin (Kitada et al., 1998), α‐synuclein (Polymeropoulos et al., 1997), and DJ‐1 (Biosa et al., 2017; Bonifati et al., 2003), are believed to leading to the occurrence of PD.