In fact, this persistent mortality risk among the septic population may be related tothe continuation of the inflammatory state that persists even after the clinicalresolution of sepsis, a risk that was unveiled in patients addmited withcommunity-acquired pneumonia.(25)In a multicenter study, GenIMS, (25) high levels of IL-6 at hospital discharge were associated witha higher 3-month mortality that may be related to a high prevalence of new orworsening cardiovascular disease, which may persist for several years.(12,26). This evidence concerns the gene IL6 and cardiovascular disorder.