The mutation of p.F464S was found in a patient with the X‐linked form of Olmsted Syndrome and the intronic mutation c.671‐9T > G of MBTPS2 was found in IFAP patient with Olmsted syndrome‐like features(Haghighi et al., 2013; Wang et al., 2014). This evidence concerns the gene MBTPS2 and Olmsted syndrome.