SIRT2 and Parkinson disease: Combining the results of miR-8061 in double luciferase assay, these results preliminarily indicate that rs2015 could influence the binding effect between miR-8061 and the 3′UTR region of SIRT2 gene, and miR-8061 could regulate SIRT2 protein expression level, which may ultimately have an effect on modulating PD pathology or risk.