We observed that the C/T+C/C genotype carriers of rs12778366 showed an elevated expression level of SIRT1 compared with TT genotype carriers in PD patients (Figure 1(c)), and the T/T carriers of rs2015 showed an increased expression level of SIRT2 compared with GG carriers (Figure 1(e)). Here, SIRT1 is linked to Parkinson disease.