ADAM12 and breast cancer: In order to explore the influence of lnc015192 and Adam12 on tumor metastasis in vivo, either lnc015192 or Adam12-deletion 4T1 cells were injected into mice models, and the results showed that a smaller number of lung metastatic focuses were induced in sh-lnc015192-injected or sh-Adam12-injected animal models than in the control group, suggesting that the loss of lnc015192 or Adam12 suppresses the invasion, migration and metastasis ability of BC cells (36).