Given that CpG oligo-deoxynucleotides (CpG ODNs) can activate the TLR9 signaling pathways effectively in human lung cancer cells, they used the miRNA microarray technique to detect the expression of miRNA of 95D cells treated or untreated with CpG ODNs and look for the differentially expressed miRNAs after treatment with CpG ODNs. The gene discussed is TLR9; the disease is lung cancer.