A meta-analysis of the FOXN3 gene (using the oncomine database) demonstrated that among 15 different malignancies (including liver cancer, lung cancer, colon cancer, prostate cancer, laryngeal cancer, glioblastoma multiform, and lymphoma) there was a very marked down-regulation of the FOXN3 gene. The gene discussed is FOXN3; the disease is malignant colon neoplasm.