We chose Alox5ap and Laptm5 to illustrate that expression profiles for the microglial gene module were similar irrespective of whether a gene has an established role in neurologic disease (e.g., Trem2 and Alox5ap) or limited to no known role (e.g., Laptm5) in neurologic disease (Table 3). Here, TREM2 is linked to nervous system disorder.