CD44 and neoplasm: In line with the increased cytokine expression (Figures 2A,B; Supplementary Figure 3A), we detected a significantly higher number of effector-memory CD4+ T cells (TEM) and TH1-like cells in the mLN of HSD fed tumor-bearing mice based on an antibody panel containing CD3, CD4, CD44, CD62L, CCR6, and CXCR3 specific antibodies by FlowSOM analysis at day 15–17 p.i. (Figure 3A).