CNR1 and triple-negative breast carcinoma: As indicated by their profile, CB1R/CB2R for para-quinones and CB2R for ortho-quinones, para-quinones (such as PM49, Table 1) inhibit prostate LNCaP cell viability through a mechanism involving oxidative stress, PPARγ, and partially CB1R (Morales et al., 2013), while ortho-quinones (such as 10, Table 1) act on triple-negative breast cancer cells via CB2R activation and ROS production (Morales et al., 2015).