TARDBP and semantic dementia: hnRNP E2 has been reported to incorporate into stress granules alongside TDP-43 (Fujimura et al., 2008; Liu-Yesucevitz et al., 2010) and in a recent pathological study hnRNP E2 was shown to colocalise with TDP-43 inclusions in FTLD cases which presented with the semantic dementia clinical phenotype (Davidson et al., 2017).