SOD1 and congestive heart failure: In a study with patients with congestive heart failure, F2-isoprostanes were higher in class III than in class II NYHA (Ney York Heart Association scale) patients, and inverse correlations between F2-isoprostanes and plasma levels of lutein, lycopene, zeaxanthin and alpha- and beta-carotene were found, which were also correlated with SOD [132].