RHOA and gastric cancer: Gene Set Enrichment Analysis (GSEA) was carried out between low FBXW5 samples and high FBXW5 samples, whereby the high FBXW5 samples were found to be enriched in gene sets related to metastasis (p-value < 0.001) (Figure 6D), RhoA signaling (p-value < 0.001) (Figure 6E) and advanced stage gastric cancer (p-value < 0.001) (Figure 6F, left panel).