Among these 26 significant probes, the change in DNA methylation of some members was reported to be potential indicators of some cancer types, such as PLEKHA6 [18], MARVELD1 [14], MST1R [19], LTBP1 [20], CLIC3 [21], SLC13A5 [22], SFRP5 [23], CPXM1 [24], and AKR1B1 [25]. The gene discussed is SFRP5; the disease is cancer.