TNF and polymyositis: The present results indicate the phenomena for the increase ofIL-10serum levels, the decreasing trend for TNF-α, the serum level of CRP found to be elevated during inflammation in tissues from the standard value (<6 mg/L) [46,47], the CK-MM level elevated from the standard value (<168 U/L) in response to muscular dystrophy, connective tissue damage, [8,9,14,50,51,52,53], and AldoA level increases from the standard value of <7.6 U/L due to skeletal muscle damages, polymyositis, dermatomyositis, muscular dystrophy, and inflammatory muscle disease and bone erosion [53] during LHD-KOA.