HBEGF and cancer: Identified genes are mainly involved in inflammation (CXCL2, CXCL5, IL6, IL10), cellular adhesion (ITGA3, ITGAV, ITGB6), tissue remodeling (CTSG, F3, PLG, SERPINE1), and extracellular matrix organization (COL1A1, COL3A1, COL5A1, COL5A2, CSF3, HBEGF, MIF, TGFA, VTN), fundamental processes in the induction of EMT and cancer progression [29,30,31,32].