Besides cell metastasis and CSC regulation, we also demonstrated enhanced cell proliferation and anchorage-independent growth of HK2 in ovarian cancer cells, in line with the well-established HK2 tumor-promoting effect observed in other cancers in vivo, such as glioblastoma [12], medulloblastoma [13], and breast cancer [14]. This evidence concerns the gene HK2 and ovarian carcinoma.