CD28 and relapsing-remitting multiple sclerosis: Moreover, the analysis of Glut1 expression on different T cell subsets in RRMS patients, revealed that Th17-like cells (CXCR3−CCR6+) expressed higher levels of Glut1 compared to Th1-like cells (CXCR3+CCR6−) or Th0-like cell (CXCR3−CCR6−) and CD28 stimulation up-regulated Glut1 expression in all T cell subsets, although to a higher extent in Th17 cells (Figure S3d,e).